Description
KPV is a tripeptide consisting of lysine, proline, and valine.
It’s a potent anti-inflammatory and healing properties, making it a promising candidate for treating a variety of conditions:
Conditions Benefited by KPV
1. Inflammatory Bowel Disease (IBD)
2. Skin Conditions
3. Wound Healing
4. Gastrointestinal Health
5. Arthritis and Joint Health
Mechanism of Action
KPV’s mechanism of action is primarily centered around its ability to modulate
inflammatory responses and promote healing. The peptide exerts its effects through
several pathways:
1. Inhibition of Pro-Inflammatory Cytokines: KPV has been shown to inhibit
the production of pro-inflammatory cytokines, such as TNF-α, IL-1β, and IL-6.
These cytokines play a critical role in the inflammatory cascade, contributing to
tissue damage and chronic inflammation.
2. Modulation of Nuclear Factor-kappa B (NF-κB) Pathway: KPV inhibits the
activation of the NF-κB pathway, a key regulator of inflammation. By
suppressing NF-κB, KPV reduces the transcription of genes involved in
inflammatory processes.
3. Promotion of Anti-Inflammatory Cytokines: KPV also promotes the
production of anti-inflammatory cytokines, such as IL-10, which help to resolve
inflammation and restore tissue homeostasis.
4. Antimicrobial Properties: KPV exhibits antimicrobial activity, which is
particularly beneficial in conditions where infection and inflammation coexist.
This property helps in reducing microbial load and subsequent inflammation.
Conditions Benefited by KPV and NAD+ Combination
1. Inflammatory Bowel Disease (IBD)
KPV: Reduces inflammation, promotes mucosal healing, and
alleviates symptoms.
NAD+: Supports cellular repair and energy metabolism,
aiding in overall gut health and reducing fatigue associated
with chronic inflammation.
2. Skin Conditions
Psoriasis and Eczema:
KPV: Reduces inflammation, restores skin barrier
function, and alleviates symptoms like redness and
itching.
NAD+: Enhances cellular repair, reduces oxidative
stress, and promotes skin health and resilience.
3. Wound Healing:
KPV: Accelerates healing, reduces scar formation
through anti-inflammatory and antimicrobial effects.
NAD+: Promotes collagen synthesis, enhances
cellular energy, and supports tissue regeneration.
4. Gastrointestinal Health
Stomach Inflammation and Lining Repair:
KPV: Repairs gastric lining and prevents further
inflammation.
NAD+: Supports cellular repair and energy
metabolism, enhancing overall gastrointestinal
function.
Gut Microbiota Balance:
KPV: Maintains gut microbiota balance through
antimicrobial properties.
NAD+: Supports gut barrier integrity and cellular
health.
5. Arthritis and Joint Health
KPV: Reduces joint inflammation, pain, and swelling by
inhibiting pro-inflammatory cytokines.
NAD+: Enhances mitochondrial function, reduces oxidative
stress, and supports cartilage integrity and joint health.
6. Neuroprotection and Cognitive Health
KPV: Reduces neuroinflammation, potentially benefiting
conditions like Alzheimer’s and multiple sclerosis.
NAD+: Supports neuronal health, enhances cognitive
function, and protects against neurodegenerative diseases.
Reviews
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