Dermatological and inflammatory disorders have various causes, and the exact factors can differ depending on the specific condition. In many cases, these disorders have a multifactorial etiology involving a combination of genetic predisposition, immune system dysfunction, environmental triggers, and lifestyle factors. Genetic factors play a significant role, as certain individuals may have a higher risk of developing these disorders due to inherited gene variants. Immune system dysfunction, including an overactive immune response or impaired immune regulation, can contribute to the development of chronic inflammation in the skin. Environmental triggers, such as allergens, irritants, pollutants, and infections, can also provoke inflammatory responses in susceptible individuals.